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Characteristics, Regional Evaluation, and D-Antigen in Transfusions by Emergency Medical Services

Key Points Question What are the patterns and regional trends of prehospital blood transfusions in civilian emergency medical services settings across the US? Findings This cohort study of 10 444 patients… Click to show full abstract

Key Points Question What are the patterns and regional trends of prehospital blood transfusions in civilian emergency medical services settings across the US? Findings This cohort study of 10 444 patients identified a significant increase in whole blood use (from 10% to 30%), along with regional differences in transfusion practices. In female patients of childbearing potential there was a marked increase (from 43% to 75%) in the proportion of emergency medical services–transfused blood that was D-positive. Meaning These findings highlight current US practice and trends while underscoring the importance of standardizing transfusion protocols.

Keywords: emergency medical; medical services; regional evaluation; characteristics regional; evaluation antigen

Journal Title: JAMA Network Open
Year Published: 2025

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