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Assessment of Demographic, Genetic, and Imaging Variables Associated With Brain Resilience and Cognitive Resilience to Pathological Tau in Patients With Alzheimer Disease

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This cross-sectional, longitudinal study of amyloid-β–positive individuals with mild cognitive impairment or Alzheimer disease dementia examines the factors associated with interindividual differences in brain and cognitive resilience to tau positron… Click to show full abstract

This cross-sectional, longitudinal study of amyloid-β–positive individuals with mild cognitive impairment or Alzheimer disease dementia examines the factors associated with interindividual differences in brain and cognitive resilience to tau positron emission tomography load and to changes in global cognition over time.

Keywords: tau; alzheimer disease; resilience; cognitive resilience; brain

Journal Title: JAMA Neurology
Year Published: 2020

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