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Prevalence of Mutations in Mendelian Stroke Genes in Early Onset Stroke Patients

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Heritability of stroke is assumed not to be low, especially in the young stroke population. However, most genetic studies have been performed in highly selected patients with typical clinical or… Click to show full abstract

Heritability of stroke is assumed not to be low, especially in the young stroke population. However, most genetic studies have been performed in highly selected patients with typical clinical or neuroimaging characteristics. We investigated the prevalence of 15 Mendelian stroke genes and explored the relationships between variants and the clinical and neuroimaging characteristics in a large, unselected, young stroke population.

Keywords: stroke genes; prevalence mutations; mutations mendelian; stroke; mendelian stroke

Journal Title: Annals of Neurology
Year Published: 2022

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