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Evaluation of Murine Macrophage Cytokine Production After In Vivo Morphine Treatment.

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The discovery of opioid receptor expression on immune cells has originated a large research activity on the possible modulation by opioid drugs of immune system responses. In this chapter we… Click to show full abstract

The discovery of opioid receptor expression on immune cells has originated a large research activity on the possible modulation by opioid drugs of immune system responses. In this chapter we describe an easy methodology useful to obtain information about the potential immunomodulatory activity of opioid drugs. An in vivo treatment schedule is used, and macrophages are studied for their ability to release different cytokines.

Keywords: macrophage cytokine; murine macrophage; treatment; evaluation murine; production vivo; cytokine production

Journal Title: Methods in molecular biology
Year Published: 2021

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