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Influenza B false-positive results by rapid molecular tests Alere™ i Influenza A&B 2 in France.

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The Alere-i™ Influenza A&B (Abbott), a nicking endonuclease amplification reaction test, has recently been improved in order to deliver results in a few minutes. Our field observation highlights two problems… Click to show full abstract

The Alere-i™ Influenza A&B (Abbott), a nicking endonuclease amplification reaction test, has recently been improved in order to deliver results in a few minutes. Our field observation highlights two problems with this new version: improper interpretation of a test as valid despite improper reagent hydration and falsely influenza B positive results. We advise users of the new system to check reagent hydration prior to reporting a result and to systematically confirm positive influenza B results.

Keywords: alere influenza; results rapid; false positive; influenza false; positive results

Journal Title: Diagnostic microbiology and infectious disease
Year Published: 2019

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