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Activation of P-TEFb by RBM7: To Live or Let Die.

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In this issue of Molecular Cell, Bugai et al. (2019) unveil that a key step of the pro-survival cellular response to a genotoxic attack is the activation of P-TEFb by RBM7.… Click to show full abstract

In this issue of Molecular Cell, Bugai et al. (2019) unveil that a key step of the pro-survival cellular response to a genotoxic attack is the activation of P-TEFb by RBM7. This crucial step triggers RNA polymerase II release from promoter-proximal pausing and expression of DNA damage response genes.

Keywords: activation tefb; live let; rbm7 live; tefb rbm7; let die

Journal Title: Molecular cell
Year Published: 2019

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