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Ruthenium(II)-catalyzed α-fluoroalkenylation of arenes via C–H bond activation and C–F bond cleavage

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Ru(II)-Catalyzed efficient α-fluoroalkenylation of arenes has been realized with gem-difluorostyrene as an olefinating reagent. This coupling system is efficient with a broad substrate scope, providing 1,2-diaryl-substituted monofluoroalkenes with good to… Click to show full abstract

Ru(II)-Catalyzed efficient α-fluoroalkenylation of arenes has been realized with gem-difluorostyrene as an olefinating reagent. This coupling system is efficient with a broad substrate scope, providing 1,2-diaryl-substituted monofluoroalkenes with good to excellent regio- and stereoselectivities under silver-free conditions.

Keywords: arenes via; bond; catalyzed fluoroalkenylation; fluoroalkenylation arenes; ruthenium catalyzed

Journal Title: Organic chemistry frontiers
Year Published: 2018

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