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Brain properties predict proximity to symptom onset in sporadic Alzheimer’s disease

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Estimated years to symptom onset (EYO) is a measurement developed to track disease progression in patients with genetic Alzheimer’s disease. Vogel et al. apply this concept to individuals with a… Click to show full abstract

Estimated years to symptom onset (EYO) is a measurement developed to track disease progression in patients with genetic Alzheimer’s disease. Vogel et al. apply this concept to individuals with a parental history of sporadic Alzheimer’s disease. A neuroimaging-based model successfully predicts EYO and years to clinical conversion in unseen data. See Tijms and Visser (doi:10.1093/brain/awy113) for a scientific commentary on this article.

Keywords: alzheimer disease; sporadic alzheimer; disease; brain properties; symptom onset

Journal Title: Brain
Year Published: 2018

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