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Role of small RNAs harbored by sperm in embryonic development and offspring phenotype

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RNA harbored by mammalian sperm is increasingly considered to be an additional source of paternal hereditary information, beyond DNA. Recent studies have demonstrated the role of sperm small noncoding RNAs… Click to show full abstract

RNA harbored by mammalian sperm is increasingly considered to be an additional source of paternal hereditary information, beyond DNA. Recent studies have demonstrated the role of sperm small noncoding RNAs (sncRNAs) in modulating early embryonic development and offspring phenotype. The biogenesis of the sperm sRNA payload of mammalian sperm has been explored in many studies.

Keywords: embryonic development; role; offspring phenotype; sperm; development offspring

Journal Title: Andrology
Year Published: 2022

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