LAUSR

UWFI with IO with scleral indentation (Mackenzie et al. 2007; Khandhadia et al. 2009). Mackenzie et al. (2007) included 93 eyes and showed a sensitivity of 45.0% and 74.0% for lesions anterior and posterior to equator, respectively, and a specificity of 85.0%. Khandhadia et al. (2009) included 246 eyes and showed a similar tendency for IO to miss peripheral holes and tears with a 33.0% specificity and a 98% specificity. In comparison with our study, Mackenzie et al. (2007) and Khandhadia et al. (2009) found worse sensitivity and specificity for peripheral changes. This difference could be explained by the use of IO with scleral indentation, a technique superior to 3M-SLB (Natkunarajah et al. 2003). Our study emphasizes that detailed examination of the fellow eye by both 3M-SLB and UWFI is important to detect changes predisposing for RRD and existing localized RRD. Our study indicates that combining UWFI with 3M-SLB provides the best potential for detecting clinically relevant changes.