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Dear Editors, The WDF channel in the Sysmex XN 1000 uses fluorescent flow cy‐ tometry to determine the white blood cell differential by plotting side scatter (SSC) optical signals on… Click to show full abstract
Dear Editors, The WDF channel in the Sysmex XN 1000 uses fluorescent flow cy‐ tometry to determine the white blood cell differential by plotting side scatter (SSC) optical signals on the X‐axis and cell fluorescence (SFL) on the Y‐axis. The NEUT‐SSC value is related to the optical sig‐ nal that depicts the internal complexity/granularity of neutrophils.1,2 Reduced neutrophil cytoplasmic granularity is seen in conditions like myelodysplastic syndrome or chronic myelomonocytic leukemia and is considered an indicator of dysplasia while during infection due to neutrophil activation, neutrophil cytoplasmic granules may increase. We undertook the following study to evaluate whether NEUT‐ SSC could be of clinical significance. Our aim for this study was twofold:
Journal Title: International Journal of Laboratory Hematology
Year Published: 2019
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