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Customizing Host Chromatin: a Bacterial Tale.

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Successful bacterial colonizers and pathogens have evolved with their hosts and have acquired mechanisms to customize essential processes that benefit their lifestyle. In large part, bacterial survival hinges on shaping… Click to show full abstract

Successful bacterial colonizers and pathogens have evolved with their hosts and have acquired mechanisms to customize essential processes that benefit their lifestyle. In large part, bacterial survival hinges on shaping the transcriptional signature of the host, a process regulated at the chromatin level. Modifications of chromatin, either on histone proteins or on DNA itself, are common targets during bacterium-host cross talk and are the focus of this article.

Keywords: microbiology; host chromatin; chromatin bacterial; customizing host; bacterial tale; host

Journal Title: Microbiology spectrum
Year Published: 2019

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