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Minimum Information for Reporting a Genomics Experiment.

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Exome and genome sequencing has facilitated the identification of hundreds of genes and other regions that are recurrently mutated in hematologic neoplasms. The datasets from these studies theoretically provide opportunities.… Click to show full abstract

Exome and genome sequencing has facilitated the identification of hundreds of genes and other regions that are recurrently mutated in hematologic neoplasms. The datasets from these studies theoretically provide opportunities. Quality differences between datasets can confound secondary analyses. We explore the consequences of these on the conclusions from some recent studies of B-cell lymphomas. We highlight the need for a minimum reporting standard to increase transparency in genomic research.

Keywords: genomics experiment; reporting genomics; information reporting; minimum information

Journal Title: Blood
Year Published: 2022

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