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Key Points • A CRISPR/Cas9 screen targeting RNA binding proteins identifies RBM12 as a novel HbF regulator.• RBM12-mediated HbF repression is BCL11A-independent and reliant on its RRM1 domain. Click to show full abstract
Key Points • A CRISPR/Cas9 screen targeting RNA binding proteins identifies RBM12 as a novel HbF regulator.• RBM12-mediated HbF repression is BCL11A-independent and reliant on its RRM1 domain.
Keywords:
characterization rbm12;
novel regulator;
identification characterization;
regulator;
rbm12 novel
Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
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Journal Title: Blood Advances
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!