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Bgb-A425, an investigational anti-TIM-3 monoclonal antibody, in combination with tislelizumab, an anti-PD-1 monoclonal antibody, in patients with advanced solid tumors: A phase I/II trial in progress.

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TPS3146Background: While immune surveillance plays a critical role in preventing tumor proliferation and metastasis, tumors develop resistance mechanisms to suppress and/or escape the immune system... Click to show full abstract

TPS3146Background: While immune surveillance plays a critical role in preventing tumor proliferation and metastasis, tumors develop resistance mechanisms to suppress and/or escape the immune system...

Keywords: anti tim; antibody; a425 investigational; investigational anti; bgb a425; monoclonal antibody

Journal Title: Journal of Clinical Oncology
Year Published: 2020

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