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Trichodysplasia Spinulosa

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Trichodysplasia spinulosa (TS) is a unique, rare clinical and histological dermatologic entity described mainly in setting of immunosuppression. It is caused by a novel human polymoavirus, trichodysplasia spinulosa-associated polyomavirus (TSPyV).… Click to show full abstract

Trichodysplasia spinulosa (TS) is a unique, rare clinical and histological dermatologic entity described mainly in setting of immunosuppression. It is caused by a novel human polymoavirus, trichodysplasia spinulosa-associated polyomavirus (TSPyV). We report a biopsy-proven case of TS in a renal transplant patient presented to dermatology outpatient clinic in Montreal, Canada in 2015. Reduction of immunosuppression and/or anti-viral therapy is the main therapeutic strategies used to treat such cases. Our patient was managed with valgancyclovir with no obvious response. Subsequently, a trial of topical imiquimod was commenced. Awareness of TS can prompt early diagnosis and management to prevent possible complications. Keywords: Trichodysplasia spinulosa, immunosuppression, organ-trasplant, human polyomavirus.

Keywords: trichodysplasia spinulosa; trichodysplasia; immunosuppression

Journal Title: Sultan Qaboos University Medical Journal
Year Published: 2023

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