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Binding of the bacterial adhesin FimH to its natural, multivalent high-mannose type glycan targets.

Multivalent carbohydrate–lectin interactions at host–pathogen interfaces play a crucial role in the establishment of infections. Although competitive antagonists that prevent pathogen adhesion are ... Click to show full abstract

Multivalent carbohydrate–lectin interactions at host–pathogen interfaces play a crucial role in the establishment of infections. Although competitive antagonists that prevent pathogen adhesion are ...

Keywords: natural multivalent; binding bacterial; fimh natural; multivalent; adhesin fimh; bacterial adhesin

Journal Title: Journal of the American Chemical Society
Year Published: 2019

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