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A major challenge for new antibiotic discovery is predicting the physicochemical properties that enable small molecules to permeate Gram-negative bacterial membranes. We have applied physicochemica... Click to show full abstract
A major challenge for new antibiotic discovery is predicting the physicochemical properties that enable small molecules to permeate Gram-negative bacterial membranes. We have applied physicochemica...
Keywords:
mechanistic characterization;
optimization mechanistic;
characterization pyridopyrimidine;
pyridopyrimidine inhibitors;
bacterial biotin;
inhibitors bacterial
Journal Title: Journal of Medicinal Chemistry
Year Published: 2019
Link to full text (if available)
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Journal Title: Journal of Medicinal Chemistry
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!