LAUSR

: Our purpose in this case report is to pay attention to an unusual presentation of HPV infection. A 27-year-old-male patient with the complaint of dysuria, hematuria, and urethral lesion was presented to the clinic. The first diagnosis was papillary urethral cancer based on the pathology report. We considered another expert's opinion from a pathologist point of view due to the report of a rare cancer for this young patient. The slides review showed no dysplastic change and confirmed condylomata acuminata. Primary urethral condyloma acuminata is rare and health care professionals should consider a thorough medical history, especially high-risk sexual behaviors of patients. Considering the risk of anogenital cancers, the type of HPV virus should also be determined in the patients.