A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models
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DOI: 10.1136/jitc-2022-004592
Abstract: Background Adenosine is a metabolite that suppresses antitumor immune response of T and NK cells via extracellular binding to the two subtypes of adenosine-2 receptors, A2ARs. While blockade of the A2AARs subtype effectively rescues lymphocyte… read more here.
Keywords: a2aar a2bar; a2bar; patient derived; lymphocyte activity ... See more keywords