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Accelerating GPCR Drug Discovery With Conformation-Stabilizing VHHs

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Published in 2022 at "Frontiers in Molecular Biosciences"

DOI: 10.3389/fmolb.2022.863099

Abstract: The human genome encodes 850 G protein-coupled receptors (GPCRs), half of which are considered potential drug targets. GPCRs transduce extracellular stimuli into a plethora of vital physiological processes. Consequently, GPCRs are an attractive drug target… read more here.

Keywords: drug discovery; pharmacology; accelerating gpcr; gpcr drug ... See more keywords