Promoter antisense RNAs: beyond transcription by-products of active promoters
Sign Up to like & getrecommendations! Published in 2022 at "RNA Biology"
DOI: 10.1080/15476286.2022.2062177
Abstract: ABSTRACT Omics-based technologies, which have developed rapidly over the last few decades, have generated increasing evidence demonstrating pervasive divergent transcription from RNA polymerase II (Pol II) promoters of eukaryotic genome, and indeed have raised considerable… read more here.
Keywords: active promoters; antisense rnas; transcription; promoter antisense ... See more keywords
A model of active transcription hubs that unifies the roles of active promoters and enhancers.
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic acids research"
DOI: 10.1093/nar/gkab235
Abstract: An essential questions of gene regulation is how large number of enhancers and promoters organize into gene regulatory loops. Using transcription-factor binding enrichment as an indicator of enhancer strength, we identified a portion of H3K27ac… read more here.
Keywords: active transcription; promoters enhancers; transcription hubs; active promoters ... See more keywords