Impact of adjuvant endocrine therapy in older patients with comorbidities and estrogen receptor‐positive, node‐negative breast cancer—A National Cancer Database analysis
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DOI: 10.1002/cncr.33489
Abstract: Data are lacking about the benefit of adjuvant endocrine therapy (ET) in older patients with multiple comorbidities. The authors sought to determine the effect of ET on the survival of older patients who had multiple… read more here.
Keywords: endocrine therapy; adjuvant endocrine; therapy older; receptor ... See more keywords
Adjuvant Endocrine Therapy.
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DOI: 10.1007/978-3-319-70197-4_2
Abstract: The use of hormonal therapy in breast cancer has improved the overall outcome for patients with early-stage hormone receptor-positive disease. The choice of hormone therapy is related to multiple factors, including menopausal state, patient preference,… read more here.
Keywords: adjuvant endocrine; hormone; endocrine therapy; cancer ... See more keywords
Oral mucosal changes induced by adjuvant endocrine therapies in breast cancer patients: clinical aspects and proposal for management
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DOI: 10.1007/s00520-020-05797-z
Abstract: Adjuvant systemic treatments in breast cancer are indicated to reduce the risk of relapse. Their systemic side effects have been well documented and include menopausal symptoms such as impaired libido and vaginal dryness, increased risk… read more here.
Keywords: adjuvant endocrine; oral mucosal; breast cancer; endocrine therapies ... See more keywords
Ductal carcinoma in situ in patients younger than 30 years: differences in adjuvant endocrine therapy and outcomes
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DOI: 10.1007/s10549-020-06014-5
Abstract: To use the National Cancer Database to assess treatment patterns in very young women with ductal carcinoma in situ (DCIS) given their propensity for higher risk features and increased risk of recurrence. We used the… read more here.
Keywords: endocrine therapy; adjuvant endocrine; treatment; group ... See more keywords
Discontinuation of adjuvant endocrine therapy and impact on quality of life and functional status in older patients with breast cancer
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DOI: 10.1007/s10549-022-06583-7
Abstract: Side effects are the main reason for discontinuation of adjuvant endocrine therapy in older adults. The aim of this study was to examine geriatric predictors of treatment discontinuation of adjuvant endocrine therapy within the first… read more here.
Keywords: therapy; functional status; adjuvant endocrine; discontinuation ... See more keywords
Treatment Decisions and Adherence to Adjuvant Endocrine Therapy in Breast Cancer
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DOI: 10.1007/s12609-017-0248-5
Abstract: Purpose of ReviewTreatment decisions regarding adjuvant endocrine therapy in breast cancer has become increasingly complex, with non-adherence to treatment one of the most crucial issues. We aimed to review the literature on both aspects focusing… read more here.
Keywords: adjuvant endocrine; endocrine therapy; breast cancer;
Cost-effectiveness Analysis of CYP2D6*10 Pharmacogenetic Testing to Guide the Adjuvant Endocrine Therapy for Postmenopausal Women with Estrogen Receptor Positive Early Breast Cancer in China
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DOI: 10.1007/s40261-019-00842-0
Abstract: A CYP2D6 gene polymorphism is related to the effect of tamoxifen treatment in patient with estrogen-receptor positive (ER) positive breast cancer and CYP2D6*10 T/T can lead to a poor prognosis in Asian patients. Although one-off… read more here.
Keywords: adjuvant endocrine; endocrine therapy; breast cancer; pharmacogenetic testing ... See more keywords
Optimizing adjuvant endocrine therapy for early ER+ breast cancer: An update for surgeons.
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DOI: 10.1016/j.amjsurg.2018.07.052
Abstract: INTRODUCTION The optimal duration of adjuvant endocrine therapy in early ER + breast cancer has been controversial. This article aims to provide an overview of the evidence. METHODS A search of the literature was conducted via MEDLINE… read more here.
Keywords: endocrine therapy; adjuvant endocrine; early breast; breast cancer ... See more keywords
Geographic disparities in adherence to adjuvant endocrine therapy in Appalachian women with breast cancer
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DOI: 10.1016/j.sapharm.2016.08.004
Abstract: Background: Appalachia is a largely rural, mountainous, poor and underserved region of the United States. Adherence to adjuvant endocrine therapy among Appalachian women with breast cancer is suboptimal. Objectives: To explore small‐area geographic variations and… read more here.
Keywords: endocrine therapy; adjuvant endocrine; breast cancer; therapy ... See more keywords
A high level of estrogen-stimulated proteins selects breast cancer patients treated with adjuvant endocrine therapy with good prognosis
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DOI: 10.1080/0284186x.2017.1324211
Abstract: Abstract Background: Adjuvant endocrine therapy has significantly improved survival of estrogen receptor α (ER)-positive breast cancer patients, but around 20% relapse within 10 years. High expression of ER-stimulated proteins like progesterone receptor (PR), Bcl-2 and… read more here.
Keywords: adjuvant endocrine; estrogen; breast cancer; cancer patients ... See more keywords
Grip Strength in Women Being Treated for Breast Cancer and Receiving Adjuvant Endocrine Therapy: Systematic Review
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DOI: 10.1093/ptj/pzx069
Abstract: Background Adjuvant endocrine therapy in breast cancer has increased survival rates; however, it is not without musculoskeletal side effects. Purpose The purpose of this review was to systematically and critically appraise the available scientific evidence… read more here.
Keywords: adjuvant endocrine; grip; grip strength; breast cancer ... See more keywords