The anterior nucleus of the thalamus plays a role in the epileptic network
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51693
Abstract: We investigated both the metabolic differences and interictal/ictal discharges of the anterior nucleus of the thalamus (ANT) in patients with epilepsy to clarify the relationship between the ANT and the epileptic network. read more here.
Keywords: nucleus thalamus; epileptic network; anterior nucleus; thalamus plays ... See more keywords
Precision of Discrete and Rhythmic Forelimb Movements Requires a Distinct Neuronal Subpopulation in the Interposed Anterior Nucleus.
Sign Up to like & getrecommendations! Published in 2018 at "Cell reports"
DOI: 10.1016/j.celrep.2018.02.017
Abstract: The deep cerebellar nuclei (DCN) represent output channels of the cerebellum, and they transmit integrated sensorimotor signals to modulate limb movements. But the functional relevance of identifiable neuronal subpopulations within the DCN remains unclear. Here,… read more here.
Keywords: distinct neuronal; precision discrete; anterior nucleus; discrete rhythmic ... See more keywords
Thalamic nuclei degeneration in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2021.05.043
Abstract: OBJECTIVES To define both the severity and extent of structural alteration in certain thalamic nuclei by means of MR morphometry and to compare these findings with clinical performance in different phenotypes of multiple sclerosis (MS).… read more here.
Keywords: thalamic nuclei; anterior nucleus; multiple sclerosis; mm3 ... See more keywords
High-frequency stimulation of anterior nucleus of thalamus desynchronizes epileptic network in humans
Sign Up to like & getrecommendations! Published in 2018 at "Brain"
DOI: 10.1093/brain/awy187
Abstract: Epilepsy has been classically seen as a brain disorder resulting from abnormally enhanced neuronal excitability and synchronization. Although it has been described since antiquity, there are still significant challenges achieving the therapeutic goal of seizure… read more here.
Keywords: anterior nucleus; stimulation; nucleus thalamus; high frequency ... See more keywords
Analysis of Deep Brain Stimulation Lead Targeting in the Stimulation of Anterior Nucleus of the Thalamus for Epilepsy Clinical Trial
Sign Up to like & getrecommendations! Published in 2021 at "Neurosurgery"
DOI: 10.1093/neuros/nyab186
Abstract: Abstract BACKGROUND Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) is an effective therapy for patients with drug-resistant focal epilepsy. Best practices for surgical targeting of the ANT can be refined… read more here.
Keywords: epilepsy; deep brain; stimulation; anterior nucleus ... See more keywords
What Should We Expect for Real-World Outcomes of Deep Brain Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy?
Sign Up to like & getrecommendations! Published in 2023 at "Neurology"
DOI: 10.1212/wnl.0000000000201455
Abstract: Neurostimulation offers a non-curative approach to treat patients with medication-resistant seizures. In the past 15 years, 2 large, well-designed randomized controlled trials (RCTs) led to the US Food and Drug Administration approval for responsive neurostimulation1… read more here.
Keywords: nucleus thalamus; stimulation anterior; deep brain; real world ... See more keywords
Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Drug-Resistant Epilepsy in the MORE Multicenter Patient Registry
Sign Up to like & getrecommendations! Published in 2023 at "Neurology"
DOI: 10.1212/wnl.0000000000206887
Abstract: Background and Objectives The efficacy of deep brain stimulation of the anterior nucleus of the thalamus (ANT DBS) in patients with drug-resistant epilepsy (DRE) was demonstrated in the double-blind Stimulation of the Anterior Nucleus of… read more here.
Keywords: nucleus thalamus; stimulation anterior; registry; drug resistant ... See more keywords
Optimal targeting of the anterior nucleus of the thalamus for epilepsy: a meta-analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurosurgery"
DOI: 10.3171/2022.2.jns212550
Abstract: OBJECTIVE Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) has been shown to be an effective therapeutic option for select patients with limbic epilepsy. However, the optimal target and electrode position… read more here.
Keywords: nucleus thalamus; dbs; meta analysis; analysis ... See more keywords