CD47-targeting antibodies as a novel therapeutic strategy in hematologic malignancies
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DOI: 10.1016/j.lrr.2021.100268
Abstract: CD47 is a surface glycoprotein expressed by host cells to impede phagocytosis upon binding to macrophage SIRPα, thereby represents an immune checkpoint known as the “don't-eat-me” signal. However, accumulating evidence shows that solid and hematologic… read more here.
Keywords: cd47 targeting; strategy hematologic; therapeutic strategy; targeting antibodies ... See more keywords