Unusual Correlation between the Apparent Amorphous Solubility of a Drug and Solubilizer Concentration Revealed by NMR Analysis.
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DOI: 10.1021/acs.molpharmaceut.2c00478
Abstract: Herein, we investigated the effect of the solubilizers, cetyltrimethylammonium bromide (CTAB) and amino methacrylate copolymer (Eudragit E PO, EUD-E), on the apparent amorphous solubility of ketoprofen (KTP) and free KTP concentrations in an aqueous phase… read more here.
Keywords: ktp; solubility; ctab; apparent amorphous ... See more keywords