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Published in 2017 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-017-1874-1
Abstract: This study describes the synthesis, pharmacological evaluation, including acetylcholinesterase (AChE)/butyrylcholinesterase (BChE) inhibition, amyloid beta (Aβ) antiaggregation, and neuroprotective effects, as well as molecular modeling of novel 2-(4-substituted phenyl)-1H-benzimidazole derivatives. These derivatives were synthesized by cyclization…
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Keywords:
arylbenzimidazole derivatives;
alzheimer disease;
novel arylbenzimidazole;
bche ... See more keywords