Metal-Free Generation of γ-Cyanoalkyl Radicals by N-Heterocyclic Carbene Catalysis: Assembly of 6-Cyanoalkyl Phenanthridines.
Sign Up to like & getrecommendations! Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c03808
Abstract: A number of γ-cyanoalkyl radicals were generated by sustainable N-heterocyclic carbene catalysis in tin-, transition-meal-, and light-free conditions, followed by insertion into biaryl isonitriles, thus leading to the rapid assembly of a variety of diversely… read more here.
Keywords: cyanoalkyl radicals; cyanoalkyl phenanthridines; cyanoalkyl; heterocyclic carbene ... See more keywords
Aryl radical-mediated N-heterocyclic carbene catalysis
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DOI: 10.1038/s41467-021-24144-2
Abstract: There have been significant advancements in radical reactions using organocatalysts in modern organic synthesis. Recently, NHC-catalyzed radical reactions initiated by single electron transfer processes have been actively studied. However, the reported examples have been limited… read more here.
Keywords: catalysis; radical mediated; carbene catalysis; mediated heterocyclic ... See more keywords
β-Sulfonylation of α-bromoenals enabled by N-heterocyclic carbene catalysis
Sign Up to like & getrecommendations! Published in 2019 at "Organic Chemistry Frontiers"
DOI: 10.1039/c9qo00956f
Abstract: An N-heterocyclic carbene (NHC)-catalyzed three-component tandem β-sulfonylation/esterification of α-bromoenals was developed. read more here.
Keywords: carbene catalysis; heterocyclic carbene; enabled heterocyclic; carbene ... See more keywords