Decoding disease-causing mechanisms of missense mutations from supramolecular structures
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DOI: 10.1038/s41598-017-08902-1
Abstract: The inheritance modes of pathogenic missense mutations are known to be highly associated with protein structures; recessive mutations are mainly observed in the buried region of protein structures, whereas dominant mutations are significantly enriched in… read more here.
Keywords: disease causing; causing mechanisms; missense mutations; decoding disease ... See more keywords