Assessing Computational Model Credibility Using a Risk-Based Framework: Application to Hemolysis in Centrifugal Blood Pumps
Sign Up to like & getrecommendations! Published in 2019 at "ASAIO Journal"
DOI: 10.1097/mat.0000000000000996
Abstract: Medical device manufacturers using computational modeling to support their device designs have traditionally been guided by internally developed modeling best practices. A lack of consensus on the evidentiary bar for model validation has hindered broader… read more here.
Keywords: credibility; centrifugal blood; risk; model ... See more keywords
Low-Cost and Compact Disposable Extracorporeal Centrifugal Blood Pump Utilizing a Homopolar Bearingless Switched Reluctance Slice Motor
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Access"
DOI: 10.1109/access.2023.3254546
Abstract: The high biocompatibility and high durability of disposable extracorporeal centrifugal blood pumps (CBPs) utilizing magnetic bearing or bearingless motor technology make them perfect for supporting cardiopulmonary circulation for patients. However, the rotor incorporated in the… read more here.
Keywords: bearingless; motor; slice motor; pump ... See more keywords
Computational Modeling of the Food and Drug Administration's Benchmark Centrifugal Blood Pump.
Sign Up to like & getrecommendations! Published in 2020 at "Artificial organs"
DOI: 10.1111/aor.13643
Abstract: In order to simulate hemodynamics within centrifugal blood pumps and to predict pump hemolysis, CFD simulations must be thoroughly validated against experimental data. They must also account for and accurately model the specific working fluid… read more here.
Keywords: pump; centrifugal blood; hemolysis; blood pump ... See more keywords
The influence of non-conformal grid interfaces on the results of large eddy simulation of centrifugal blood pumps.
Sign Up to like & getrecommendations! Published in 2022 at "Artificial organs"
DOI: 10.1111/aor.14263
Abstract: BACKGROUND Computational fluid dynamics has been widely used to assist the design and evaluation of blood pumps. Discretization errors associated with computational grid may influence the credibility of numerical simulations. Non-conformal grid interfaces commonly exist… read more here.
Keywords: non conformal; blood pumps; grid interfaces; centrifugal blood ... See more keywords
Development of the Centrifugal Blood Pump for a Hybrid Continuous Flow Pediatric Total Artificial Heart: Model, Make, Measure
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.886874
Abstract: Clinically-available blood pumps and total artificial hearts for pediatric patients continue to lag well behind those developed for adults. We are developing a hybrid, continuous-flow, magnetically levitated, pediatric total artificial heart (TAH). The hybrid TAH… read more here.
Keywords: development; total artificial; flow; pump ... See more keywords
A comprehensive comparison of the in vitro hemocompatibility of extracorporeal centrifugal blood pumps
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1136545
Abstract: Purpose: Blood damage has been associated with patients under temporary continuous-flow mechanical circulatory support. To evaluate the side effects caused by transit blood pumping, in vitro hemocompatibility testing for blood damage in pumps is considered… read more here.
Keywords: hemocompatibility; blood pumps; vitro hemocompatibility; blood ... See more keywords
Optimization of a Screw Centrifugal Blood Pump Based on Random Forest and Multi-Objective Gray Wolf Optimization Algorithm
Sign Up to like & getrecommendations! Published in 2023 at "Micromachines"
DOI: 10.3390/mi14020406
Abstract: The centrifugal blood pump is a commonly used ventricular assist device. It can replace part of the heart function, pumping blood throughout the body in order to maintain normal function. However, the high shear stress… read more here.
Keywords: optimization; screw centrifugal; blood pump; blood ... See more keywords