Complete Chemical Synthesis of Minimal Messenger RNA by Efficient Chemical Capping Reaction.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.1c00996
Abstract: Site-specific chemical modification of mRNA can improve its translational efficiency and stability. For this purpose, it is desirable to develop a complete chemical synthesis method for chemically modified mRNA. The key is a chemical reaction… read more here.
Keywords: reaction; complete chemical; capping reaction; chemical ... See more keywords
Complete chemical structures of human mitochondrial tRNAs
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DOI: 10.1038/s41467-020-18068-6
Abstract: Mitochondria generate most cellular energy via oxidative phosphorylation. Twenty-two species of mitochondrial (mt-)tRNAs encoded in mtDNA translate essential subunits of the respiratory chain complexes. mt-tRNAs contain post-transcriptional modifications introduced by nuclear-encoded tRNA-modifying enzymes. They are… read more here.
Keywords: mitochondrial trnas; human mitochondrial; trna modifications; chemical structures ... See more keywords
All-in-one NMR spectroscopy of small organic molecules: complete chemical shift assignment from a single NMR experiment
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra03417g
Abstract: A new class of NOAH NMR experiments (NOAH-AST and NOAH-ASTPS), with the abbreviations, A: 1,1-ADEQUATE, S: sensitivity improved version of multiplicity-edited (ME)-HSQC, T: TOCSY, and TPS: pure shift TOCSY, are reported to obtain complete chemical… read more here.
Keywords: small organic; chemical shift; organic molecules; spectroscopy ... See more keywords