Stereospecific Construction of Quaternary Carbon Stereocenters from Quaternary Carbon Stereocenters
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c01695
Abstract: Organoaluminum species promote a smooth nucleophilic substitution at the quaternary carbon stereocenter of stereodefined polysubstituted cyclopropyl methyl phosphate with a complete inversion of configuration, even when more reactive functional groups are present. The regio- and… read more here.
Keywords: carbon; quaternary carbon; carbon stereocenters; stereocenters quaternary ... See more keywords
Enantioselective construction of quaternary tetrahydropyridines by palladium-catalyzed vinylborylation of alkenes.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc01488k
Abstract: Here, the highly enantioselective construction of 3,3-disubstituted tetrahydropyridines via Pd(0)-catalyzed asymmetric vinylborylation of (Z)-1-iodo-dienes and B2pin2 in the presence of a (S)-p-CF3-BnPHOX ligand is reported. This process is supposed to be initiated by oxidative addition… read more here.
Keywords: tetrahydropyridines palladium; construction; enantioselective construction; construction quaternary ... See more keywords