Permanent neuroglial remodeling of the retina following infiltration of CSF1R inhibition-resistant peripheral monocytes
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1807123115
Abstract: Significance This work contributes to the understanding of the enigmatic progressive retinal damage following acute ocular surface injury. Clinical findings in patients suggest that such injuries can adversely affect the retina. This study demonstrates that… read more here.
Keywords: peripheral monocytes; infiltration; csf1r inhibition; injury ... See more keywords
CSF2-STAT5 Signaling in TAMs Contributes to CSF1R Inhibition Resistance.
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DOI: 10.1158/2159-8290.cd-rw2021-155
Abstract: CSF1R inhibition combined with STAT5 blockade normalized TAM phenotype and sustained tumor control. read more here.
Keywords: csf2 stat5; stat5 signaling; signaling tams; inhibition ... See more keywords
Proliferation and Differentiation in the Adult Subventricular Zone Are Not Affected by CSF1R Inhibition
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2019.00097
Abstract: Microglia are reported to have significant roles in regulating normal mammalian adult neurogenesis. There are two neurogenic niches in the adult mammal brain: the subgranular zone (SGZ) in the hippocampus, and the subventricular zone (SVZ),… read more here.
Keywords: subventricular zone; zone; adult; csf1r inhibition ... See more keywords