Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures
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DOI: 10.1038/s41467-021-25284-1
Abstract: Between 10 and 20 million people worldwide are infected with the human T-cell lymphotropic virus type 1 (HTLV-1). Despite causing life-threatening pathologies there is no therapeutic regimen for this deltaretrovirus. Here, we screened a library… read more here.
Keywords: htlv; structural basis; basis inhibition; deltaretroviral intasome ... See more keywords