Preparation of amorphous solid dispersions by cryomilling: chemical and physical concerns related to APIs and carriers.
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DOI: 10.1021/acs.molpharmaceut.9b01265
Abstract: In this work, a chemical and physical evaluation of cryogenic milling to manufacture amorphous solid dispersions (ASDs) is provided to support novel mechanistic insights in the cryomilling process. Cryogenic milling devices are considered as reactors… read more here.
Keywords: dispersions cryomilling; solid dispersions; chemical physical; amorphous solid ... See more keywords