Retromer dysfunction in amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2118755119
Abstract: Significance Amyotrophic lateral sclerosis is an adult-onset paralytic disorder whose mechanism remains uncertain. In this work, we report a defect in the retromer complex, which plays a crucial role in endosomal protein sorting and trafficking… read more here.
Keywords: retromer; dysfunction amyotrophic; lateral sclerosis; retromer dysfunction ... See more keywords
Autonomic dysfunction in amyotrophic lateral sclerosis: A neurophysiological and neurosonology study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Neuroimaging"
DOI: 10.1111/jon.12993
Abstract: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder affecting upper and lower motor neurons. Some ALS patients exhibit concomitant nonmotor signs, and thus ALS is considered a multisystem disorder. The aim of this study… read more here.
Keywords: dysfunction amyotrophic; autonomic dysfunction; lateral sclerosis; study ... See more keywords