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Published in 2022 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.2c00458
Abstract: The emerging proteolysis targeting antibodies (PROTABs) offer an attractive technology that circumvents some of the challenges of small-molecule intracellular degraders with limited bioavailability and cell permeability. PROTABs present an improved approach to target degradation of…
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Keywords:
antibodies protabs;
emerging proteolysis;
protabs application;
targeting antibodies ... See more keywords