Thiol-ene Enabled Chemical Synthesis of Truncated S-Lipidated Teixobactin Analogs
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DOI: 10.3389/fchem.2020.00568
Abstract: Herein is described the introduction of lipid moieties onto a simplified teixobactin pharmacophore using a modified Cysteine Lipidation on a Peptide or Amino acid (CLipPA) technique, whereby cysteine was substituted for 3-mercaptopropionic acid (3-MPA). A… read more here.
Keywords: enabled chemical; teixobactin; thiol ene; chemical synthesis ... See more keywords