LAUSR

Evolving cryo-EM structural approaches for GPCR drug discovery.

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2 Published in 2021 at "Structure"

DOI: 10.1016/j.str.2021.04.008

Abstract: G protein-coupled receptors (GPCRs) are the largest class of cell surface drug targets. Advances in stabilization of GPCR:transducer complexes, together with improvements in cryoelectron microscopy (cryo-EM) have recently been applied to structure-assisted drug design for… read more here.

Keywords: cryo structural; evolving cryo; gpcr drug; drug ... See more keywords