Mitochondrial ROS Triggers KIN Pathogenesis in FAN1-Deficient Kidneys
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DOI: 10.3390/antiox12040900
Abstract: Karyomegalic interstitial nephritis (KIN) is a genetic adult-onset chronic kidney disease (CKD) characterized by genomic instability and mitotic abnormalities in the tubular epithelial cells. KIN is caused by recessive mutations in the FAN1 DNA repair… read more here.
Keywords: deficient kidneys; dna damage; kidney; fan1 ... See more keywords