Articles with "feature pharmacophore" as a keyword



Discovery of novel MurB inhibitors through common feature pharmacophore–based virtual screening and in vitro biological evaluation

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Published in 2025 at "Journal of the Chinese Chemical Society"

DOI: 10.1002/jccs.70127

Abstract: MurB, a key enzyme involved in bacterial cell wall synthesis, has become an important target in antibacterial drug research due to its crucial role in inhibiting peptidoglycan biosynthesis. In this study, a virtual screening workflow… read more here.

Keywords: virtual screening; evaluation; vitro biological; feature pharmacophore ... See more keywords