Crystallizable Fragment Glycoengineering for Therapeutic Antibodies Development
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DOI: 10.3389/fimmu.2017.01554
Abstract: Monoclonal antibody (mAb)-based therapeutics are the fastest growing class of human pharmaceuticals. They are typically IgG1 molecules with N-glycans attached to the N297 residue on crystallizable fragment (Fc). Different Fc glycoforms impact their effector function,… read more here.
Keywords: therapeutic antibodies; crystallizable fragment; fragment glycoengineering; glycoengineering therapeutic ... See more keywords