Methylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancers
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DOI: 10.1038/s41598-019-45346-1
Abstract: Mutations in isocitrate dehydrogenases 1 and 2 (IDHmut) are present in a variety of cancers, including glioma, acute myeloid leukemia (AML), melanoma, and cholangiocarcinoma. These mutations promote hypermethylation, yet it is only a favorable prognostic… read more here.
Keywords: gliomas; gliomas compared; idh mutant; transcription patterns ... See more keywords