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   Articles with "gstt1 gstm1" as a keyword



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Genotoxicity of inhalational anesthetics and its relationship with the polymorphisms of GSTT1, GSTM1, and GSTP1 genes

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recommendations! Published in 2018 at "Environmental Science and Pollution Research"

DOI: 10.1007/s11356-018-3859-0

Abstract: Due to their wide applications, concern exists regarding possible genotoxic effects of inhalational anesthetics (IAs) among operating room personnel. This study was undertaken to examine genotoxic properties of co-exposure to nitrous oxide, sevoflurane, and isoflurane… read more here.

Keywords: gstt1 gstm1; gstp1; gstt1; inhalational anesthetics ... See more keywords

Cancer risk and nullity of Glutathione-S-transferase mu and theta 1 in occupational pesticide workers.

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recommendations! Published in 2021 at "Current pharmaceutical biotechnology"

DOI: 10.2174/1389201022666210810092342

Abstract: Occupational exposure to pesticides has been associated with adverse health conditions, including genotoxicity and cancer. Nullity of GSTT1/GSTM1 increases the susceptibility of pesticide workers to these adverse health effects due to lack of efficient detoxification… read more here.

Keywords: gstt1 gstm1; pesticide workers; cancer risk; cancer ... See more keywords

Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia.

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recommendations! Published in 2022 at "Current cancer drug targets"

DOI: 10.2174/1568009623666221027103845

Abstract: The objective of our research was to clarify the role of genetic polymorphisms in GST (T1 and M1) in the development of Ph-ve CML. MATERIALS AND METHODS We report on a case-control study, with 126… read more here.

Keywords: impact gstt1; statistically significant; gstm1; gstt1 gstm1 ... See more keywords
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The Association of GSTT1, GSTM1, and TNF-α Polymorphisms With the Risk and Outcome in Multiple Myeloma

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recommendations! Published in 2019 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2019.01056

Abstract: Oxidative stress and systemic inflammation are closely linked with increased risk of cancer development. Tumor necrosis factor alpha (TNF-α) is one of the pro-inflammatory cytokines. Glutathione S-transferases (GSTs) are enzymes involved in oxidative stress handling.… read more here.

Keywords: risk; gstm1; gstt1 gstm1; risk outcome ... See more keywords