HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia‐like animals
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.25914
Abstract: Although histone acetylation is one of the most widely studied epigenetic modifications, there is still a lack of information regarding how the acetylome is regulated during brain development and pathophysiological processes. We demonstrate that the… read more here.
Keywords: h3k9; schizophrenia like; acetylation; differentiation ... See more keywords
Selective Inhibition of HDAC1 and HDAC3 Inhibits Survival of Diffuse Large Cell Lymphoma Via Epigenetic Modulation of Death Associated Protein (DAPK)
Sign Up to like & getrecommendations! Published in 2017 at "Blood"
DOI: 10.1182/blood.v130.suppl_1.4020.4020
Abstract: Histone deacetylases (HDACs) are key players of epigenetic regulation of gene expression and are therefore attractive targets for cancer therapy. Many epigenetic drugs including HDAC inhibitors (HDACi) have shown anti-tumor activity in several types of… read more here.
Keywords: hdac1 hdac3; cell lymphoma; hdac1; hdac3 ... See more keywords