MiR-223-3p regulates erythropoiesis by targeting TGFBR3/Smad signaling pathway in hemoglobin H-Constant Spring disease
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Medicine"
DOI: 10.1080/07853890.2025.2530690
Abstract: Abstract Background MicroRNAs (miRNAs) have emerged as regulators of pathogenesis in hematopoiesis by targeting post-transcription mRNA regulation. However, the involvement of miRNAs in hemoglobin H-Constant Spring (HbH-CS) disease remains unclear. The present study analyzed miRNAs… read more here.
Keywords: disease; mir 223; hemoglobin constant; constant spring ... See more keywords
Presentation of Compound Heterozygous Hemoglobin Constant Spring and Hemoglobin Pakse in Neonates
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Pediatric Hematology/Oncology"
DOI: 10.1097/mph.0000000000001406
Abstract: Background: Mutations causing α thalassemia are divided into deletion and nondeletion groups. In the nondeletion group, hemoglobin constant spring (Hb CS) and hemoglobin Pakse (Hb Pakse) are both caused by a termination codon mutation leading… read more here.
Keywords: compound heterozygous; hemoglobin; constant spring; pakse ... See more keywords