Metabolism and Hepatotoxicity of Pyrazinamide, an Antituberculosis Drug
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DOI: 10.1124/dmd.121.000389
Abstract: Pyrazinamide (PZA) is an important component of a standard combination therapy against tuberculosis. However, PZA is hepatotoxic, and the underlying mechanisms are poorly understood. Biotransformation of PZA in the liver was primarily suggested behind its… read more here.
Keywords: metabolism; metabolism hepatotoxicity; hepatotoxicity; drug metabolism ... See more keywords