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Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6518-2_17
Abstract: In mammals, gene expression is largely controlled at the transcriptional level. In response to environmental or intrinsic signaling, gene expression is often fine-tuned by epigenetic modifications, including DNA methylation and histone modifications. One such histone…
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Keywords:
histone ubiquitination;
vitro assay;
assay study;
histone ... See more keywords
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Published in 2022 at "Cancer research"
DOI: 10.1158/0008-5472.can-21-2106
Abstract: Osteosarcoma is the most common malignancy of the bone, yet the survival for osteosarcoma patients is virtually unchanged over the past 30 years. This is principally because development of new therapies is hampered by a…
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Keywords:
m6a rna;
rna methylation;
growth;
histone ubiquitination ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158187
Abstract: Cells are constantly exposed to numerous genotoxic stresses that induce DNA damage. DNA double-strand breaks (DSBs) are among the most serious damages and should be systematically repaired to preserve genomic integrity. The efficiency of repair…
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Keywords:
histone ubiquitination;
dna damage;
ubiquitination;
repair ... See more keywords