Human Serotonin Transporter Coding Variation Establishes Conformational Bias with Functional Consequences.
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DOI: 10.1021/acschemneuro.8b00689
Abstract: The antidepressant-sensitive serotonin (5-HT) transporter (SERT) dictates rapid, high-affinity clearance of the neurotransmitter in both the brain and periphery. In a study of families with multiple individuals diagnosed with autism spectrum disorder (ASD), we previously… read more here.
Keywords: serotonin transporter; human serotonin; sert; coding variation ... See more keywords