Hypermutator strains of Pseudomonas aeruginosa reveal novel pathways of resistance to combinations of cephalosporin antibiotics and beta-lactamase inhibitors
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DOI: 10.1371/journal.pbio.3001878
Abstract: Hypermutation due to DNA mismatch repair (MMR) deficiencies can accelerate the development of antibiotic resistance in Pseudomonas aeruginosa. Whether hypermutators generate resistance through predominantly similar molecular mechanisms to wild-type (WT) strains is not fully understood.… read more here.
Keywords: hypermutator strains; pseudomonas aeruginosa; mmr deficient; beta lactamase ... See more keywords